2role of molecular shape and liquid structure
Báo cáo y học: "Synergistic role of c-Myc and ERK1/2 in the mitogenic response to TGF-1 in cultured rat nucleus pulposus cells" ppsx
... quantifying DNA Effects of inhibition of c-Myc transcriptional activity and inhibition of ERK1/2 activity in the presence of ng/mL TGF1 were determined After serum deprivation, 79.0% of nucleus pulposus ... the analysis of 10,000 events The histograms present typical results and the percentage of cells in G0/G1, S and G2/M phases are shown as the average of duplicated measurements Page of 12 (page ... report cell cycle arrest accompanied by suppression of c-Myc mRNA in lymphoma [56] and the suppression of c-Myc with upregulation of levels of p21 and p27 in myeloid leukemia [57,58] These reports...
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The role of nitric oxide and prostaglandin e2 in prolonged hemorrhagic shock 2
... consisted of mL of hypnorm (Jansen Pharmaceutica, Beerse, Belgica), which contained 0.315 mg of fentanyl and 10 mg of fluanisone, and mL of midazolam (Roche, Basel, Switzerland) which contained mg of ... shock model: The role of NO and PGE2 and the therapeutics effects of conservative fluids, NOS and COX-2 inhibitors 45 4.1 Introduction The up-regulation of nitric oxide (NO) and cyclooxgenase-2 ... up-regulation as a result of an inflammatory response (Tsukada et al., 2000, Knoferl et al., 2001) Two isoforms of COX have been identified namely COX-1 and COX-2 COX-1 is a constitutive isoform that is...
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Tài liệu Báo cáo khoa học: Structural effects of a dimer interface mutation on catalytic activity of triosephosphate isomerase The role of conserved residues and complementary mutations pptx
... subunit dissociation [27] and also in maintaining the geometry of the active site The availability of crystal structures of TIMs from 21 sources and the large database of TIM sequences from various ... 5.5 and w = )144.1 7.0 [53] The distribution of the / and w values of all other Lys residues in the TIM structure is shown for comparison The possible role of energetically unfavorable Ramachandran ... between K12 and the side chains of N10 and Q64, which maintain the unusual Ramachandran angles for the K12 residue, and a Ramachandran scatter plot for the K12 residues in 21 TIM structures from...
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Tài liệu Báo cáo khoa học: Role of hydroxyl group and R/S configuration of isostere in binding properties of HIV-1 protease inhibitors docx
... atoms of Phe53 and Phe153) In the case of Ôwide tunnelÕ, the diameter of the effective view through the ˚ solvent channel is 12.4 A (measured as a distance of projections of opposite Sd atoms of ... of isostere in inhibitors OE, RE and SE in complex with HIV-1 protease Diagram shows schematically the structure of inhbitors and measured torsion angles X ¼ H; (R) OH and (S) OH for OE, RE and ... groups of the isostere The changes of torsion angles in the isostere also resulted in shifts of Ca of Phe in P1¢ position of the OE ˚ inhibitor by 0.58 and 0.46 A in comparison with SE and RE...
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Tài liệu Báo cáo khoa học: "Applications of GPC Rules and Character Structures in Games for Learning Chinese Characters" doc
... for learners of various alphabetic languages (Jared et al., 1990; Ziegler and Goswami, 2005) and of Chinese, e.g., (Lee et al., 2005), and is important for both young readers (Ho and Bryant, 1997; ... Tzeng, and D.-L Hung 2005 Consistency, regularity, and frequency effects in naming Chinese characters, Language and Linguistics, 6(1), 75–107 C.-H Lin and P Collins 2012 The effects of L1 and orthographic ... time of logging into the game, players can choose two parameters: (1) class level: lower class (i.e., grades and 2), middle class (i.e., grades and 4), or upper class (i.e., grades and 6) and...
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Báo cáo khoa học: The role of helix 8 and of the cytosolic C-termini in the internalization and signal transduction of B1 and B2 bradykinin receptors potx
... in Role of helix and C-termini in bradykinin receptors receptor signaling because: (a) interruption of the amphipathic structure of B1wt helix in B1wt and B1KB2 through the presence of a serine ... proposed that activation of the receptor, and subsequently of the G protein, leads to a change in the environment of helix resulting in the loss of the helical structure Mutation of specific residues ... min) that was comparable to that of B1CB2 and B1YB2 (Fig 2B) Agonist-induced internalization of modified B1KB2 constructs Phosphorylation patterns of B2wt and of B1 ⁄ B2 chimeras reflect their...
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Role of an electrolyte and substrate on the stability of porous silicon
... nanoscale structure of PS leads to an enormous increase in surface area and the presence of large number of unpaired bonds at the surface which alter the surface recombination rates and consequently ... degradation of stability of PS on electrolyte (HF–C2H5OH and HF–H2O2) and current density formed on textured and polished Si substrates, respectively The emphasis is mainly 265 on the development of PS ... electrolytes The first is a mixture of HF and C2H5OH (1:1 by volume) which is almost universally used [1] and would be abbreviated as electrolyte A The second is a mixture of HF and H2O2 (1:1 by volume)...
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Báo cáo khoa học: "Analysis System of Speech Acts and Discourse Structures Using Maximum Entropy Model*" pptx
... model are worse than the results of each analysis model For top-1 candidate, the performance of the speech act analysis fell off about 2.89% and that of the discourse structure analysis about 7.07% ... 3, utterance and belong to the same discourse segment So the DSB of utterance becomes DC Since a sub-dialogue of one level (i.e., the DS 1.1.2) consisting of utterances and ends, and new sub-dialogue ... relationship of discourse between two 236 consecutive utterances in a dialogue and used them for statistically analyzing both the speech act of an utterance and the discourse structure of a dialogue...
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Daptomycin for Treatment of Complicated Skin and Skin Structure Infections pot
... diagnosis and management of skin and soft-tissue infections Clin Infect Dis 2005;41(10):1373–406 May AK, et al Treatment of Complicaed Skin and Soft Tissue Infections Surg Infect 2009;10(5):467–99 Anderson ... skin and skin structure infections—developing antimicrobial drugs for treatment 1998 Arbeit RD, et al The safety and efficacy of daptomycin for the treatment of complicated skin and skin -structure ... of .500 IU/L compared to standard treatment (9.5% of 116 vs 1.5% of 111, P = 0.04) However, only three of these patients required discontinuation of daptomycin.62 A retrospective analysis of...
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Báo cáo khoa học: The role of residues R97 and Y331 in modulating the pH optimum of an insect b-glycosidase of family 1 pdf
... 3.64 A and the distance between the tyrosine and glutamate varies from 2.59 to 2.98 A Discussion An inspection of the three-dimensional structure of some family b-glycosidases [1013] and of the ... R97K, Y331F and E187D) were expressed as recombinant proteins in Escherichia coli The general shape and volume of residues 97 and 331 side chains are conserved in the mutants R97M and Y331F, but ... deglycosylation) of the hydrolysis of MUbglc by the mutant enzymes is rate-limiting, no hypothesis on the effect of R97 and Y331 on the rate constant of each step can be advanced ể FEBS 2003 Mechanism of...
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Báo cáo khoa học: Dissecting the role of protein–protein and protein–nucleic acid interactions in MS2 bacteriophage stability potx
... presence of both DNA and bis-ANS decreased the stability of the protein (Fig 7B) Effects of high temperature on the secondary and tertiary structure of dlFG and sc-dlFG in the absence and presence of ... et al Fig Urea and guanidine treatment of dlFG and sc-dlFG in the presence of bis-ANS (A) Effects of increasing urea concentrations on the spectral center of mass of (m) dlFG and (r) sc-dlFG ... protein–RNA and protein–protein interactions in virus stability, measuring the effects of urea, GdnHCl and high pressure on the structure and stability of whole particles (bacteriophage MS2 and VLPs) and...
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Báo cáo khoa học: Role of the N- and C-terminal regions of the PufX protein in the structural organization of the photosynthetic core complex of Rhodobacter sphaeroides pptx
... PMC1, PMC2, PMC3 and PMC4 represent LH2, LH1 Ôempty ringsÕ, LH1–RC monomers and LH1–RC dimers, respectively A consequence of the deletion of the pufX gene is the lack of LH1–RC dimer bands in the ... Only the small molecular weight region is shown In Fig 5A, lanes and 3, corresponding to PMC3 from PufXD2)4 and PufXD2)7, respectively, above the dominant LH1 a and b bands, a band attributable ... a faint band, attributable to PufXD2)19 is indicated by an arrow, while no band, except those of LH1 a and b, can be seen in the mutant PufXD2)26 and in the PufDX strain Table Summary of experimental...
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delphi - the tomes of delphi - algorithms and data structures
... Tomes of Delphi Algorithms and Data Structures Julian Bucknall Wordware Publishing, Inc Library of Congress Cataloging-in-Publication Data Bucknall, Julian Tomes of Delphi: algorithms and data structures ... out of the user and producing some kind of output for her The standard algorithms have been developed and refined by computer scientists for use in the programming trenches by the likes of you and ... the basics of standard algorithms and data structures Indeed, looking at the code should teach such a programmer many tips and tricks of the advanced programmer The more advanced structures can...
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the role of labour mobility and informal networks for knowledge transfer
... number and concentration of permanent links 199 Dispersion as a function of the number and concentration of permanent links 200 Expertise as a function of the number and concentration of permanent ... company is shaped by the experience trajectory of the scientist They apply the framework of Stephan and Levin (1991) and Levin and Stephan (1991), which focuses on the incentive and reward structure ... Two Faces of R&D Economic Journal, 99(3), 569-596 Cohen, W M and Levin, R.C (1989) Empirical Studies of Innovation and Market Structure In Schmalensee, R and Willig, R (Eds.) Handbook of Industrial...
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Báo cáo hóa học: " The role of feed-forward and feedback processes for closed-loop prosthesis control" doc
... to PC software Position sensors were attached to the thumb and forefinger, the wrist and the base of the object, to enable accurate Saunders and Vijayakumar Journal of NeuroEngineering and Rehabilitation ... Multifunction prostheses of the future offer increased dexterity and functionality at the expense of additional feedforward and feedback demands (as discussed in [37]) Tasks Page 11 of 12 involving dynamic ... Saunders and Vijayakumar Journal of NeuroEngineering and Rehabilitation 2011, 8:60 http://www.jneuroengrehab.com/content/8/1/60 hardware and developed the software and firmware required for control of...
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